[Optical coherence tomography in diagnosis of intracranial hypertension in children].

Abstract

UNLABELLED:

Intracranial hypertension (IH) is important cause of optic disc edema. It is essential to distinguish the primary and secondary causes of IH. Persistent increasement of intracranial pressure over 200-250 mmH2O is caused by impairment of the balance between production and absorption of cerebrospinal fluid. Though the exact mechanism of IH is still unknown.

PURPOSE:

Assessment of usefulness of spectral optical coherence tomography with dual beam eye tracking (SLO/OCT) in diagnosis of intracranial hypertension in children.

MATERIALS AND METHODS:

4 children (at the age of 3-12 years) with IH underwent an comprehensive ophthalmological examination, including visual acuity testing (Snellen charts), color vision (Ishihara charts), evaluation of anterior and posterior segment of the eye in slit lamp. On SLO/OCT (Spectralis, Heidelberg) scans RNFL profile of the optic disc was assessed at admission day and after 8 weeks of treatment with oral diuretics. In all patients MRI of the central nervous system was performed.

RESULTS:

In all children best corrected visual acuity and MRI scans were normal. 3 of 4 patients had secondary IH. Median global RNFL was 273 microm at admission day. In 3 of 4 children remission of optic disc edema was observed after 8 weeks of treatment with diuretics - median global RNFL was 138 microm.

CONCLUSIONS:

Diagnosis of intracranial hypertension requires interdisciplinary cooperation. SLO/OCT is useful in monitoring remission of the optic disc edema.

• Authors: Małgorzata Mrugacz, Michał Szumiński, Alina Bakunowicz-Łazarczyk
• Journal: Klinika oczna (Klin Oczna) Vol. 113 Issue 7-9 Pg. 258-62 ( 2011) ISSN: 0023-2157 [Print] Poland
• Vernacular Title: Optyczna koherentna tomografia w diagnostyce nadciśnienia wewnatrzczaszkowego u dzieci i młodziezy.
• PMID: 22256569 (Publication Type: English Abstract, Journal Article)

Chemical References

• Diuretics

Topics

• Child
• Child, Preschool
• Diuretics (administration & dosage)
• Female
• Humans
• Intracranial Hypertension (diagnosis, drug therapy)
• Intraocular Pressure
• Male
• Poland
• Reproducibility of Results
• Sensitivity and Specificity
• Tomography, Optical Coherence (methods)
• Treatment Outcome
• Vision Tests (methods)
• Visual Acuity
• Visual Fields