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[Botulinum toxin A: analgesic treatment for temporomandibular joint disorders].

AbstractINTRODUCTION:
Pain, along with clicking, sub-luxation, and blocking, is one of the main symptoms for patients presenting with temporomandibular joint disorders. We assessed the effectiveness of botulinum toxin A (BOTOX(®), Allergan) as analgesic treatment for temporomandibular joint disorders.
PATIENTS AND METHOD:
Twenty-six patients with chronic pain linked to temporomandibular joint disorders were prospectively assessed. Botulinum toxin A was injected in masseter and temporalis muscles. Follow-up parameters, at one and three months, were: measuring mouth opening and diduction, muscle tenderness and pain using a visual analogue scale.
RESULTS:
There was a significant (P<0.0001) decrease of pain, an increased mouth opening, and diduction at three months. Seventy percent of the patients felt less muscle tenderness. The patient felt his psychological state had improved and so did his family.
DISCUSSION:
Botulinum toxin A significantly decreases pain and improves movements of patients presenting with temporomandibular joint disorders. The effects are prolonged three months after the injection.
AuthorsC Denglehem, J-M Maes, G Raoul, J Ferri
JournalRevue de stomatologie et de chirurgie maxillo-faciale (Rev Stomatol Chir Maxillofac) Vol. 113 Issue 1 Pg. 27-31 (Feb 2012) ISSN: 1776-257X [Electronic] France
Vernacular TitleToxine botulinique de type A : traitement antalgique des dysfonctions de l'appareil manducateur.
PMID22240328 (Publication Type: Clinical Trial, Journal Article)
CopyrightCopyright © 2012 Elsevier Masson SAS. All rights reserved.
Chemical References
  • Analgesics
  • Botulinum Toxins, Type A
Topics
  • Adolescent
  • Adult
  • Aged
  • Analgesia (methods)
  • Analgesics (therapeutic use)
  • Botulinum Toxins, Type A (therapeutic use)
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pain (drug therapy, epidemiology)
  • Pain Measurement
  • Temporomandibular Joint Disorders (complications, drug therapy, epidemiology)
  • Young Adult

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