Creutzfeldt-Jakob disease in a recipient of human pituitary-derived gonadotrophin.

Abstract	A forty-year-old female presented with an unsteady gait 13 years after receiving an eight-month course of human pituitary-derived gonadotrophin injections as treatment for infertility. Over the next ten months the patient subsequently developed generalised myoclonic jerks and dementia and finally died. Neuropathological examination revealed changes in the brain consistent with Creutzfeldt-Jakob disease. This is the first reported case of Creutzfeldt-Jakob disease in a recipient of human derived gonadotrophin.
Authors	J I Cochius, R J Burns, P C Blumbergs, K Mack, C P Alderman
Journal	Australian and New Zealand journal of medicine (Aust N Z J Med) Vol. 20 Issue 4 Pg. 592-3 (Aug 1990) ISSN: 0004-8291 [Print] Australia
PMID	2222355 (Publication Type: Case Reports, Journal Article)
Chemical References	Gonadotropins, Pituitary
Topics	Adult Creutzfeldt-Jakob Syndrome (pathology, physiopathology, transmission) Female Gonadotropins, Pituitary (adverse effects, therapeutic use) Humans Infertility, Female (drug therapy)

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