Abstract | PURPOSE: To assess the in vitro susceptibility of Streptococcus pneumoniae, Staphylococcus aureus and coagulase-negative staphylococci (CoNS) ocular isolates to antibiotics, and identify changing trends in resistance over a 10-year period. METHODS: All isolates from ocular infections collected between 2000 and 2009 were prospectively tested against several antibiotics in vitro. S. pneumoniae isolates (n = 93) were tested against 20 and S. aureus (n = 120) and CoNS (n = 214) against 19 antibiotics. To identify changes in susceptibility patterns, we compared results from 2000-2004 with those from 2005-2009. We also compared the antibiotic susceptibilities against aminoglycosides and quinolones between methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aureus (MSSA) isolates. RESULTS: All S. pneumoniae isolates were susceptible to quinolones, and 99% were susceptible to chloramphenicol. Regarding S. aureus, we noted a significant increase in resistance against penicillin in recent years (p = 0.016). Over 90% of S. aureus isolates were susceptible to quinolones and aminoglycosides. MRSA isolates were more resistant to ciprofloxacin and ofloxacin than MSSA isolates were (p = 0.016). Concerning CoNS, a significant increase in susceptibility to amikacin was noted in the second study period (p = 0.01). CONCLUSION:
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Authors | Elpis Mantadakis, Sofia Maraki, Lambros Michailidis, Zoe Gitti, Ioannis G Pallikaris, George Samonis |
Journal | Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
(J Microbiol Immunol Infect)
Vol. 46
Issue 1
Pg. 41-7
(Feb 2013)
ISSN: 1995-9133 [Electronic] England |
PMID | 22209987
(Publication Type: Journal Article)
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Copyright | Copyright © 2011. Published by Elsevier B.V. |
Chemical References |
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Topics |
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Anti-Bacterial Agents
(pharmacology)
- Child
- Child, Preschool
- Conjunctivitis
(microbiology)
- Female
- Greece
- Humans
- Infant
- Keratitis
(microbiology)
- Male
- Microbial Sensitivity Tests
- Middle Aged
- Pneumococcal Infections
(microbiology)
- Prospective Studies
- Staphylococcal Infections
(microbiology)
- Staphylococcus
(drug effects, isolation & purification)
- Streptococcus pneumoniae
(drug effects, isolation & purification)
- Young Adult
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