Abstract | CONCLUSIONS: Because the presented data reveal an immediate and persistent reduction of vertigo and a clear improvement in hearing function and functional scales, we conclude tenotomy to be effective in unilateral, definite Meniere's disease - laying the foundation for future prospective, randomized controlled trials. OBJECTIVES: This study compares the unique long-term results of tenotomy of the stapedius and tensor tympani muscles in definite Meniere's disease refractory to medical treatment and presents a hypothesis on why tenotomy seems effective. METHODS: This was an interventional cohort study. The study sample comprised 30 patients (15 males, 15 females; average age 57 ± 13.1 years) with definite Meniere's disease (AAO-HNS criteria, 1995). Patients were evaluated pre- and postoperatively using pure tone audiometry, AAO-HNS questionnaires regarding vertigo attacks, functional level scores, and tinnitus, and were followed up for 2-9 years. Postoperative values were calculated for the patient collective as a whole and consequently divided into three equal postoperative terms of 3 years each. RESULTS: A statistically significant improvement of inner ear hearing levels postoperatively (p = 0.041) and a major reduction in vertigo attacks in all groups (p < 0.001) with complete absence of attacks in 26/30 patients was noted. Results remained constant up to 9 years postoperatively. Although tinnitus persisted, the intensity was lower overall (p = 0.013).
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Authors | Benjamin Loader, David Beicht, Jafar-Sasan Hamzavi, Peter Franz |
Journal | Acta oto-laryngologica
(Acta Otolaryngol)
Vol. 132
Issue 5
Pg. 491-7
(May 2012)
ISSN: 1651-2251 [Electronic] England |
PMID | 22201453
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Audiometry, Pure-Tone
- Ear, Middle
(surgery)
- Female
- Follow-Up Studies
- Hearing
(physiology)
- Humans
- Male
- Meniere Disease
(complications, physiopathology, surgery)
- Middle Aged
- Stapedius
(surgery)
- Surveys and Questionnaires
- Tenotomy
(methods)
- Tensor Tympani
(physiopathology, surgery)
- Time Factors
- Treatment Outcome
- Vertigo
(etiology, physiopathology, surgery)
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