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Lacosamide use in refractory idiopathic primary generalized epilepsy.

Abstract
Treatment of refractory idiopathic primary generalized epilepsy can be very challenging, with limited drug options, especially in young women of childbearing age. Here we describe the cases of two young women with refractory idiopathic primary generalized epilepsy refractory to multiple antiepileptic drugs in monotherapy or combination before achieving a long-term remission with adjunctive lacosamide (LCS) treatment. Larger, randomized prospective studies are necessary to establish the effectiveness of lacosamide in these patients.
AuthorsAndro Zangaladze, Christopher Skidmore
JournalEpilepsy & behavior : E&B (Epilepsy Behav) Vol. 23 Issue 1 Pg. 79-80 (Jan 2012) ISSN: 1525-5069 [Electronic] United States
PMID22197124 (Publication Type: Case Reports, Journal Article)
CopyrightCopyright © 2011. Published by Elsevier Inc.
Chemical References
  • Acetamides
  • Anticonvulsants
  • Lacosamide
Topics
  • Acetamides (therapeutic use)
  • Anticonvulsants (therapeutic use)
  • Drug Therapy, Combination
  • Epilepsy (drug therapy)
  • Female
  • Humans
  • Lacosamide
  • Young Adult

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