Abstract | BACKGROUND: AIMS: METHODS: Between May 2007 to December 2008, 67 consecutive patients with diabetic foot ulcers were randomly assigned to VAC therapy (Group 1, n : 30) or standart wound care (Group 2, n : 37). The SF-36 questionnaire was administered the day before and in the month following wound healing. Global analyses of the 8 domains and 2 comprehensive indexes of SF-36, Physical Component Summary (PCS) and Mental Component Summary (MCS) were performed. Clinical measures included standard antidiabetic treatment, daily wound care including antiseptic bath, debridement, toe removal for gangrene when necessary, and wound care with conventional methods or VAC. Healing time was calculated as the time from hospital admission to the time of re-epithelization. RESULTS: There were no differences in the mean age, ulcer size and pulse status of the patients in both groups. Healing time in the VAC group was significantly reduced (p < 0.05). All 8 domains of SF-36 and MCS and PCS scores improved remarkably after VAC therapy. CONCLUSION:
Vacuum Assisted Closure therapy was found to be effective in the treatment of chronic diabetic ulcers. The improvement of quality of life demonstrates a clear-cut indication in this particular group of patients.
|
Authors | O Karatepe, I Eken, E Acet, O Unal, M Mert, B Koc, S Karahan, U Filizcan, M Ugurlucan, M Aksoy |
Journal | Acta chirurgica Belgica
(Acta Chir Belg)
2011 Sep-Oct
Vol. 111
Issue 5
Pg. 298-302
ISSN: 0001-5458 [Print] England |
PMID | 22191131
(Publication Type: Journal Article, Randomized Controlled Trial)
|
Topics |
- Aged
- Diabetic Foot
(physiopathology, therapy)
- Female
- Health Status Indicators
- Humans
- Male
- Middle Aged
- Negative-Pressure Wound Therapy
- Quality of Life
- Wound Healing
(physiology)
|