Abstract |
Spindle Cell Carcinoma (SPCC) is a relatively rare tumour that is classified as a subtype of squamous cell carcinoma (SCC). Histologically, SPCC is composed of a SCC region and epithelium-derived spindle cells with mesenchymal differentiation. We encountered an interesting case of multiple cancer including SPCC. A histopathologically atypical papillary lesion was found 13 years before our initial examination. Multiple verrucous leukoplakia later developed in the oral mucosa, for which an oral vitamin A derivative (a retinoid) was intermittently administered. Multiple cancer including SPCC subsequently developed in the lower gingiva. We investigated the case histologically and immunohistologically based on the concept of field cancerization.
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Authors | Hideharu Kato, Jouji Nomura, Yoshihiko Matsumura, Shigeaki Yanase, Kaori Miyahara, Rina Matsuura, Toshiro Tagawa |
Journal | Journal of maxillofacial and oral surgery
(J Maxillofac Oral Surg)
Vol. 9
Issue 2
Pg. 213-7
(Jun 2010)
ISSN: 0974-942X [Electronic] India |
PMID | 22190791
(Publication Type: Case Reports)
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