Clinical outcome of skin yaws lesions after treatment with benzathinebenzylpenicillin in a pygmy population in Lobaye, Central African Republic.

Abstract

BACKGROUND:

Yaws is a bacterial skin and bone infectious disease caused by Treponema pallidum pertenue. It is endemic, particularly among pygmies in Central African Republic. To assess the clinical cure rate after treatment with benzathinepenicillin in this population, we conducted a cohort survey of 243 patients in the Lobaye region.

FINDINGS AND CONCLUSION:

The rate of healing of lesions after 5 months was 95.9%. This relatively satisfactory level of therapeutic response implies that yaws could be controlled in the Central African Republic. Thus, reinforcement of the management of new cases and of contacts is suggested.

• Authors: Alexandre Manirakiza, Susana Vilas Boas, Narcisse Beyam, Germain Zadanga, François Xavier Konamna, Siméon P Njuimo, Rémi Laganier
• Journal: BMC research notes (BMC Res Notes) Vol. 4 Pg. 543 (Dec 15 2011) ISSN: 1756-0500 [Electronic] England
• PMID: 22171605 (Publication Type: Journal Article)