Tuberculoid leprosy and cytomegalovirus retinitis as immune restoration disease in a patient with AIDS.

Abstract

Here we report a unique case of tuberculoid leprosy and cytomegalovirus retinitis in a 27-year-old female patient with AIDS, suggestive of highly active antiretroviral therapy (HAART)-induced immune restoration disease. After initiation of HAART, the patient presented with decreased visual acuity, hypoesthetic patch with local nerve thickening, and an increase in her CD4+ T cell count. On further investigations cytomegalovirus retinitis and tuberculoid leprosy were confirmed. To our knowledge no case with such a co-existence has previously been reported.

• Authors: Shishir Kumar, Manab Kumar Ghosh, Somenath Sarkar, Sudeshna Mallik, Pradyot Narayan Biswas, Bibhuti Saha
• Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases (Int J Infect Dis) Vol. 16 Issue 2 Pg. e146-8 (Feb 2012) ISSN: 1878-3511 [Electronic] Canada
• PMID: 22169463 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2011 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

Topics

• AIDS-Related Opportunistic Infections (chemically induced, immunology, microbiology, virology)
• Acquired Immunodeficiency Syndrome (drug therapy, immunology, microbiology, virology)
• Adult
• Antiretroviral Therapy, Highly Active (adverse effects)
• Cytomegalovirus Retinitis (chemically induced, immunology, microbiology, virology)
• Female
• Humans
• Immune Reconstitution Inflammatory Syndrome (chemically induced, immunology, microbiology, virology)
• Leprosy, Tuberculoid (chemically induced, immunology, virology)