Abstract |
The effect of low doses of aspirin on women with mild pregnancy-induced hypertension was investigated by means of a prospective, randomized, double-blind trial. Forty-seven women hospitalized at 30-36 weeks' gestation because of mild pregnancy-induced hypertension were treated by a daily dose of either 100 mg aspirin or placebo. The mean blood pressure values, rates of development of severe preeclampsia, gestational ages at delivery, newborn weights, and 5-minute Apgar scores were similar in the aspirin-treated and the placebo-treated groups. We conclude that low-dose aspirin is not curative but is essentially a preventive treatment which, in order to be effective, should be started weeks before clinical signs of preeclampsia are present.
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Authors | E Schiff, G Barkai, G Ben-Baruch, S Mashiach |
Journal | Obstetrics and gynecology
(Obstet Gynecol)
Vol. 76
Issue 5 Pt 1
Pg. 742-4
(Nov 1990)
ISSN: 0029-7844 [Print] United States |
PMID | 2216216
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
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Chemical References |
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Topics |
- Adult
- Aspirin
(administration & dosage, therapeutic use)
- Double-Blind Method
- Female
- Humans
- Hypertension
(drug therapy)
- Pre-Eclampsia
(prevention & control)
- Pregnancy
- Pregnancy Complications, Cardiovascular
(drug therapy)
- Prospective Studies
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