Abstract | BACKGROUND: METHODS: We studied 57 morbidly obese patients who had mild or severe postprandial HTG after fat overload (<30 mg/dL or >90 mg/dL increase in triglycerides, respectively). All the patients underwent bariatric surgery. After surgery, the anthropometric and biochemical variables and the Homeostasis Model Assessment of Insulin Resistance were measured for 1 year at 0, 15, 30, 45, 90, 180, and 365 days after surgery. RESULTS: The patients with more severe postprandial HTG had a greater percentage of change in the Homeostasis Model Assessment of Insulin Resistance at 30, 90, and 180 days after surgery than the patients with less severe postprandial HTG. Multiple regression analysis showed that the postprandial triglyceride levels predict the variation in the Homeostasis Model Assessment of Insulin Resistance index, more so than did traditional variables, such as anthropometric, inflammatory, or hormonal data. CONCLUSION:
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Authors | Francisco J Tinahones, Maria Isabel Queipo-Ortuño, Mercedes Clemente-Postigo, Diego Fernnadez-Garcia, Geltrude Mingrone, Fernando Cardona |
Journal | Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
(Surg Obes Relat Dis)
2013 Mar-Apr
Vol. 9
Issue 2
Pg. 213-8
ISSN: 1878-7533 [Electronic] United States |
PMID | 22153002
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2013 American Society for Metabolic and Bariatric Surgery. Published by Elsevier Inc. All rights reserved. |
Chemical References |
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Topics |
- Bariatric Surgery
(methods)
- Biliopancreatic Diversion
(methods)
- Diabetes Complications
(metabolism, surgery)
- Dietary Fats
(administration & dosage)
- Female
- Homeostasis
(physiology)
- Humans
- Hypertriglyceridemia
(prevention & control)
- Insulin Resistance
(physiology)
- Male
- Obesity, Morbid
(metabolism, surgery)
- Postprandial Period
(physiology)
- Prospective Studies
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