[Sneddon syndrome: cardiac pathology and anti-phospholipid antibodies].

Abstract

Besides cerebrovascular pathology and livedo, cardiac affections are introduced in clinical manifestations of Sneddon's syndrome. They involve coronary heart disease (up to development of MI), murmur (usually mitral), occasional cardiac arrhythmia. Patients with coronary disease and cardiac murmur show antibodies to cardiolipin significantly more frequently. The role of antibodies to cardiolipin in the genesis of cardiac alterations in Sneddon's syndrome is open to discussion.

• Authors: L A Kalashnikova, E L Nasonov, V V Borisenko, V B Isman, A E Kushekbaeva, V Iu Kovalev, L Z Prudnikova
• Journal: Klinicheskaia meditsina (Klin Med (Mosk)) Vol. 68 Issue 6 Pg. 37-41 (Jun 1990) ISSN: 0023-2149 [Print] Russia (Federation)
• Vernacular Title: Sindrom Sneddona: kardial'naia patologiia i antifosfolipidnye antitela.
• PMID: 2214636 (Publication Type: English Abstract, Journal Article)

Chemical References

• Autoantibodies
• Cardiolipins

Topics

• Adolescent
• Adult
• Autoantibodies (analysis, immunology)
• Autoimmune Diseases (etiology, immunology)
• Cardiolipins (immunology)
• Cerebrovascular Disorders (complications, immunology)
• Coronary Disease (etiology, immunology)
• Cyanosis (complications, immunology)
• Female
• Humans
• Male
• Middle Aged
• Skin Diseases (immunology)
• Syndrome