Abstract | AIM: The aim of this study was to investigate the expression levels of hepatocyte growth factor (HGF) and thrombospondin-1 (TSP-1) with the clinical pathological factors in ovarian cancer, and the correlation between HGF and TSP-1 expression at the protein level. MATERIAL AND METHODS: Immunohistochemistry was applied to detect the location and expression of HGF and TSP-1 protein in ovarian cancer and benign ovarian tumor tissue. Real-time quantitative polymerase chain reaction was applied to detect HGF and TSP-1 gene mRNA expression in ovarian cancer and benign ovarian tumor tissue. RESULTS: CONCLUSION:
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Authors | Wei Wei, Beihua Kong, Xun Qu |
Journal | The journal of obstetrics and gynaecology research
(J Obstet Gynaecol Res)
Vol. 38
Issue 1
Pg. 57-64
(Jan 2012)
ISSN: 1447-0756 [Electronic] Australia |
PMID | 22136730
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | © 2011 The Authors. Journal of Obstetrics and Gynaecology Research © 2011 Japan Society of Obstetrics and Gynecology. |
Chemical References |
- Thrombospondin 1
- Hepatocyte Growth Factor
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Topics |
- Adenoma
(metabolism, pathology)
- Adult
- Carcinoma
(metabolism, pathology)
- Female
- Hepatocyte Growth Factor
(metabolism)
- Humans
- Middle Aged
- Ovarian Neoplasms
(metabolism, pathology)
- Ovary
(metabolism, pathology)
- Thrombospondin 1
(metabolism)
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