Abstract |
A 28-day-old infant developed lethargy, hypotonia, and hypothermia following a phenobarbital overdose secondary to a pharmacist's error. He was treated with multiple dose activated charcoal (MDAC) and alkalinization of the urine, which resulted in prompt recovery with rapid elimination of the drug (t1/2-11.2 hours, expected 45 to 118 hours). The use of MDAC in this newborn was safe and effective. We suggest that age should not pose a barrier to the use of MDAC, when indicated.
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Authors | Y Amitai, Y Degani |
Journal | The Journal of emergency medicine
(J Emerg Med)
1990 Jul-Aug
Vol. 8
Issue 4
Pg. 449-50
ISSN: 0736-4679 [Print] United States |
PMID | 2212564
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Charcoal
- Sorbitol
- Phenobarbital
|
Topics |
- Charcoal
(therapeutic use)
- Epilepsy
(drug therapy)
- Humans
- Infant, Newborn
- Male
- Medication Errors
- Phenobarbital
(poisoning, therapeutic use)
- Poisoning
(therapy)
- Sorbitol
(administration & dosage)
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