Abstract | PURPOSE: SUBJECTS: Convenience sample of 47 neonates, 31 to 35 weeks' gestational age. DESIGN: Double-blind, randomized controlled trial. MAIN OUTCOME MEASURE: Changes in pain response during and after an arterial puncture. METHODS: Infants were randomly assigned to receive a 24% sucrose solution or usual care (comfort measures only) 2 minutes before an arterial puncture. Pain, heart rate, and oxygen saturation were measured before, during, and after an arterial puncture. Chi-square analysis was used to determine group differences, with P < .05 considered significant. RESULTS: Forty-seven subjects were studied during arterial puncture ( sucrose, 24; no sucrose, 23). Neonates receiving sucrose solution had significantly less crying than the no sucrose group, both during and immediately after an arterial puncture (P = .006 and .022, respectively). No significant changes in other pain subscales, heart rate, or oxygen saturation were found during or after the arterial puncture (P > .05). CONCLUSION: This study found a significant reduction in the crying subscale of the Neonatal Infant Pain subscale immediately after the introduction of an arterial needle in neonates receiving a 24% sucrose solution, compared with those who did not receive sucrose solution. While prior studies found a similar reduction in pain scores after heel and venipuncture needlesticks, this is the first study evaluating a high concentration of oral sucrose to blunt the pain associated with an arterial puncture.
|
Authors | Wendy Milazzo, Janie Fielder, Angela Bittel, Jennifer Coil, Michelle McClure, Penny Tobin, Val Vande Kamp |
Journal | Advances in neonatal care : official journal of the National Association of Neonatal Nurses
(Adv Neonatal Care)
Vol. 11
Issue 6
Pg. 406-11
(Dec 2011)
ISSN: 1536-0911 [Electronic] United States |
PMID | 22123473
(Publication Type: Journal Article, Randomized Controlled Trial)
|
Chemical References |
|
Topics |
- Administration, Oral
- Arteries
- Crying
- Double-Blind Method
- Humans
- Infant, Newborn
- Intention to Treat Analysis
- Midwestern United States
- Pain
(drug therapy)
- Pain Management
(methods)
- Pain Measurement
(methods)
- Premature Birth
- Punctures
(methods)
- Sucrose
(administration & dosage, therapeutic use)
- Treatment Outcome
|