Abstract |
In the 1980s the outcome of patients with herpes simplex encephalitis was shown to be dramatically improved with aciclovir treatment. Delays in starting treatment, particularly beyond 48 h after hospital admission, are associated with a worse prognosis. Several comprehensive reviews of the investigation and management of encephalitis have been published. However, their impact on day-to day clinical practice appears to be limited. The emergency management of meningitis in children and adults was revolutionised by the introduction of a simple algorithm as part of management guidelines. In February 2008 a group of clinicians met in Liverpool to begin the development process for clinical care guidelines based around a similar simple algorithm, supported by an evidence base, whose implementation is hoped would improve the management of patients with suspected encephalitis.
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Authors | T Solomon, B D Michael, P E Smith, F Sanderson, N W S Davies, I J Hart, M Holland, A Easton, C Buckley, R Kneen, N J Beeching, National Encephalitis Guidelines Development and Stakeholder Groups |
Journal | The Journal of infection
(J Infect)
Vol. 64
Issue 4
Pg. 347-73
(Apr 2012)
ISSN: 1532-2742 [Electronic] England |
PMID | 22120595
(Publication Type: Journal Article, Practice Guideline, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2012. Published by Elsevier Ltd. |
Chemical References |
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Topics |
- Adult
- Antiviral Agents
(therapeutic use)
- Disease Management
- Encephalitis, Herpes Simplex
(drug therapy)
- Encephalitis, Viral
(diagnosis, epidemiology, pathology, therapy)
- Humans
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