Topical flurbiprofen: an effective treatment for episcleritis?

Abstract

Topical flurbiprofen was compared with placebo and prednisolone 0.3% in the treatment of episcleritis by a randomised double-blind trial. Seventy-seven eyes were included in the trial. Rapid spontaneous improvement in symptoms and signs was noted in the majority of cases. There was no significant difference between the cure-rates of patients treated with flurbiprofen and placebo over a 3-week trial period. The proportion of patients treated with prednisolone 0.3% who were cured was significantly higher than in either of the other groups after 3 weeks.

• Authors: C J Lyons, K N Hakin, P G Watson
• Journal: Eye (London, England) (Eye (Lond)) Vol. 4 ( Pt 3) Pg. 521-5 ( 1990) ISSN: 0950-222X [Print] England
• PMID: 2209920 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)

Chemical References

• Flurbiprofen

Topics

• Administration, Topical
• Adult
• Aged
• Double-Blind Method
• Female
• Flurbiprofen (administration & dosage, therapeutic use)
• Humans
• Male
• Middle Aged
• Scleritis (drug therapy)