Massive, painful tumoral calcinosis in a long-term hemodialysis patient.

Abstract

In chronic dialysis patients, ectopic, extraosseous calcifications can cause significant morbidity. Uremic tumoral calcinosis is an uncommon and severe complication of dialysis therapy. It is defined as deposition of dense nodular calcium-containing masses surrounding the large joints of the body, generally associated with the presence of high serum calcium-and-phosphorus product. We describe a 69-year-old woman submitted to long-term chronic hemodialysis that developed painful, bilateral hip tumors. Radiographic investigation showed extensive periarticular calcifications, and a bone biopsy was suggestive of adynamic bone disease and contained substantial amounts of aluminum. The lesions were surgically excised, and the histological analysis demonstrated amorphous, calcified material associated with densely collagenized connective tissue.

• Authors: Mauricio Carvalho, Igor Alexandre Côrtes de Menezes, Miguel Carlos Riella
• Journal: Hemodialysis international. International Symposium on Home Hemodialysis (Hemodial Int) Vol. 15 Issue 4 Pg. 577-80 (Oct 2011) ISSN: 1542-4758 [Electronic] Canada
• PMID: 22093521 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2011 The Authors; Hemodialysis International © 2011 International Society for Hemodialysis.

Chemical References

• Phosphorus
• Calcium

Topics

• Aged
• Arthralgia (blood, diagnostic imaging, etiology, surgery)
• Calcinosis (blood, diagnostic imaging, etiology, surgery)
• Calcium (blood)
• Female
• Humans
• Kidney Failure, Chronic (blood, therapy)
• Neoplasms, Connective Tissue (blood, diagnostic imaging, surgery)
• Phosphorus (blood)
• Radiography
• Renal Dialysis