Management of sulfur mustard-induced chronic pruritus: a review of clinical trials.

Abstract

Skin is among the most heavily damaged organs upon sulfur mustard (SM) exposure. Chronic complications due to SM-induced dermatotoxicity are quite frequent among intoxicated patients. Nevertheless, the exact pathophysiology of SM-induced chronic cutaneous complications has not been well clarified yet. The present review highlights clinically important findings on the management of SM-induced chronic skin complications with a particular focus on pruritus as the most prevalent symptom that has a significant impact on patients' quality of life. Some methodological pitfalls that implicate the validity of the trials have also been identified.

• Authors: Yunes Panahi, Amir Sarayani, Fatemeh Beiraghdar, Mojtaba Amiri, Seyed Masoud Davoudi, Amirhossein Sahebkar
• Journal: Cutaneous and ocular toxicology (Cutan Ocul Toxicol) Vol. 31 Issue 3 Pg. 220-5 (Sep 2012) ISSN: 1556-9535 [Electronic] England
• PMID: 22085409 (Publication Type: Journal Article, Review)

Chemical References

• Mustard Gas

Topics

• Chronic Disease
• Clinical Trials as Topic
• Humans
• Mustard Gas (toxicity)
• Pruritus (chemically induced)