Cryogun cryotherapy for oral leukoplakia.

Abstract

BACKGROUND:

Our previous study showed that cotton-swab cryotherapy is an alternative treatment modality for oral leukoplakia.

METHODS:

This study used liquid nitrogen spray with a cryogun (cryogun cryotherapy) to treat 60 oral leukoplakia lesions.

RESULTS:

Complete regression was achieved in all 60 oral leukoplakia lesions after cryogun cryotherapy. We found that 60 oral leukoplakia lesions treated with cryogen cryotherapy needed significantly fewer mean treatments (3.1 ± 1.3) to achieve complete regression than 60 previously reported oral leukoplakia lesions treated with cotton-swab cryotherapy (mean, 6.3 ± 3.8 treatments). Oral leukoplakia lesions on oral mucosal sites other than the tongue, <2 cm(2) , with epithelial dysplasia, or with a surface keratin thickness <55 μm required significantly fewer cryogun cryotherapy treatments to achieve complete regression.

CONCLUSIONS:

For treatment of oral leukoplakia, the cryogun cryotherapy needed fewer mean treatments to achieve complete regression of the lesions than the cotton-swab cryotherapy.

• Authors: Hung-Pin Lin, Hsin-Ming Chen, Shih-Jung Cheng, Chuan-Hang Yu, Chun-Pin Chiang
• Journal: Head & neck (Head Neck) Vol. 34 Issue 9 Pg. 1306-11 (Sep 2012) ISSN: 1097-0347 [Electronic] United States
• PMID: 22084001 (Publication Type: Journal Article)
• Copyright: Copyright © 2011 Wiley Periodicals, Inc.

Topics

• Adult
• Aged
• Aged, 80 and over
• Cryotherapy (instrumentation, methods)
• Female
• Humans
• Leukoplakia, Oral (pathology, therapy)
• Male
• Middle Aged
• Mouth Mucosa (pathology)