Abstract |
Patients rarely consult physicians before developing coagulopathy or bleeding in most reported cases of superwarfarin intoxication. A 57-year-old woman ingested red-dyed pellets of anticoagulant rodenticide containing difethialone and warfarin as well as tablets of nitrazepam. Although she presented to the hospital in a comatose state, notable pink-colored excreta hinted at the consumption of anticoagulant rodenticide, which led to the early diagnosis of superwarfarin intoxication. Supplementation of large doses of intravenous and oral vitamin K successfully prevented coagulopathy and bleeding. On the other hand, temporary and reversible myocardial suppression was extremely severe, and required the introduction of percutaneous cardiopulmonary support.
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Authors | Yoshito Kamijo, Chie Sato, Kuniko Yoshimura, Kazui Soma |
Journal | Internal medicine (Tokyo, Japan)
(Intern Med)
Vol. 50
Issue 22
Pg. 2819-22
( 2011)
ISSN: 1349-7235 [Electronic] Japan |
PMID | 22082896
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- 4-Hydroxycoumarins
- Anticoagulants
- Coloring Agents
- Rodenticides
- Vitamin K
- Warfarin
- Nitrazepam
- bromfenacoum
- difethialone
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Topics |
- 4-Hydroxycoumarins
(administration & dosage, toxicity)
- Anticoagulants
(administration & dosage, toxicity)
- Cardiomyopathies
(chemically induced, diagnosis, therapy)
- Coloring Agents
(administration & dosage)
- Female
- Humans
- Intra-Aortic Balloon Pumping
- Middle Aged
- Nitrazepam
(administration & dosage, toxicity)
- Rodenticides
(administration & dosage, toxicity)
- Vitamin K
(administration & dosage, therapeutic use)
- Warfarin
(administration & dosage, toxicity)
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