Zoon's plasma cell balanitis: a report of two cases treated with pimecrolimus.

Abstract

UNLABELLED:

Initially called (in French) "Balanoposthite chronique circonscrite benigne a plasmocytes", Zoon's plasma cell balanitis is a chronic inflammatory dermatosis affecting the glans and foreskin of uncircumcised men. The different treatment options for this condition often present partial results. Reports have shown therapeutic success using topical tacrolimus. We report the use of pimecrolimus, a homologue of tacrolimus, with good response. Two male patients diagnosed with Zoon's plasma cell balanitis, confirmed by biopsy, were subjected to daily treatment with topical pimecrolimus1%. Significant improvement was noted in patient 1 after 6 weeks and after 8 weeks in patient 2.

CONCLUSION:

Pimecrolimus cream may be an option for the treatment of this disease.

• Authors: Livia Delgado, Hebert Roberto Clivati Brandt, Damaris G Ortolan, Régia Celli Ribeiro Patriota, Paulo Ricardo Criado, Walter Belda Junior
• Journal: Anais brasileiros de dermatologia (An Bras Dermatol) 2011 Jul-Aug Vol. 86 Issue 4 Suppl 1 Pg. S35-8 ISSN: 1806-4841 [Electronic] Spain
• PMID: 22068766 (Publication Type: Case Reports, Journal Article)

Chemical References

• Dermatologic Agents
• pimecrolimus
• Tacrolimus

Topics

• Administration, Topical
• Adult
• Balanitis (drug therapy, pathology)
• Dermatologic Agents (therapeutic use)
• Humans
• Male
• Middle Aged
• Plasma Cells
• Tacrolimus (analogs & derivatives, therapeutic use)
• Treatment Outcome