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Treatment of peristomal pyoderma gangrenosum with topical crushed dapsone.

Abstract
A 27-year-old male with a history of Crohn's disease was treated for chronic pyoderma gangrenosum at his stoma site. Treatment with topical application of crushed dapsone resulted in improvement of his pyoderma gangrenosum. Crushed dapsone may be an efficacious treatment with minimal systemic side effects. This appears to be the first case of pyoderma gangrenosum treated with crushed dapsone.
AuthorsMarc Z Handler, Heather Hamilton, Daniel Aires
JournalJournal of drugs in dermatology : JDD (J Drugs Dermatol) Vol. 10 Issue 9 Pg. 1059-61 (Sep 2011) ISSN: 1545-9616 [Print] United States
PMID22052278 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Anti-Infective Agents
  • Dapsone
Topics
  • Administration, Cutaneous
  • Adult
  • Anti-Infective Agents (administration & dosage, adverse effects, therapeutic use)
  • Dapsone (administration & dosage, adverse effects, therapeutic use)
  • Follow-Up Studies
  • Humans
  • Ileostomy (adverse effects)
  • Male
  • Pyoderma Gangrenosum (drug therapy, pathology)
  • Treatment Outcome

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