Physical properties of root cementum: part 20. Effect of fluoride on orthodontically induced root resorption with light and heavy orthodontic forces for 4 weeks: a microcomputed tomography study.

Abstract

INTRODUCTION:

The major side effect of orthodontic treatment is orthodontically induced inflammatory root resorption. Fluoride was previously shown to reduce the volume of the root resorption craters in rats. However, the effect of fluoride on orthodontically induced inflammatory root resorption in humans has not yet been investigated. The aim of this study was to investigate the effect of high and low amounts of fluoride intake from birth on orthodontically induced inflammatory root resorption under light (25 g) and heavy (225 g) force applications.

METHODS:

Forty-eight patients who required maxillary premolar extractions as part of their orthodontic treatment were selected from 2 cities in Turkey with high and low fluoride concentrations in the public water of ≥ 2 and ≤ 0.05 ppm, respectively. The patients were randomly separated into 4 groups of 12 each: group 1, high fluoride intake and heavy force; group 2, low fluoride intake and heavy force; group 3, high fluoride intake and light force; and group 4, low fluoride intake and light force. Light or heavy buccal tipping orthodontic forces were applied on the maxillary first premolars for 28 days. At day 28, the teeth were extracted, and the samples were analyzed with microcomputed tomography.

RESULTS:

Fluoride reduced the volume of root resorption craters in all groups; however, this effect was significantly different with high force application (P = 0.015). It was also found that light forces caused less root resorption than heavy forces. There was no statistical difference in the amount of root resorption observed on root surfaces (buccal, lingual, mesial, and distal) in all groups. However, the middle third of the roots showed the least root resorption. With high fluoride intake and heavy force application, less root resorption was found in all root surfaces and root thirds.

CONCLUSIONS:

Fluoride may reduce the volume of root resorption craters. This effect is significant with heavy force applications (P <0.05). The cervical and apical thirds of the root showed significantly greater root resorption after the application of buccal tipping force for 4 weeks.

• Authors: Ersan Ilsay Karadeniz, Carmen Gonzales, Oyku Nebioglu-Dalci, Dennis Dwarte, Tamer Turk, Devrim Isci, Aynur M Sahin-Saglam, Huseyin Alkis, Selma Elekdag-Turk, M Ali Darendeliler
• Journal: American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics (Am J Orthod Dentofacial Orthop) Vol. 140 Issue 5 Pg. e199-210 (Nov 2011) ISSN: 1097-6752 [Electronic] United States
• PMID: 22051498 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
• Copyright: Copyright © 2011 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

Chemical References

• Alloys
• Cariostatic Agents
• Dental Alloys
• titanium molybdenum alloy
• Fluorides

Topics

• Adolescent
• Alloys (chemistry)
• Bicuspid (surgery)
• Biomechanical Phenomena
• Cariostatic Agents (administration & dosage)
• Child
• Dental Alloys (chemistry)
• Dental Cementum (drug effects, pathology)
• Female
• Fluoridation
• Fluorides (administration & dosage)
• Humans
• Image Processing, Computer-Assisted (methods)
• Imaging, Three-Dimensional (methods)
• Male
• Orthodontic Brackets
• Orthodontic Wires
• Root Resorption (etiology, pathology, prevention & control)
• Serial Extraction
• Stress, Mechanical
• Time Factors
• Tooth Apex (drug effects, pathology)
• Tooth Cervix (drug effects, pathology)
• Tooth Movement Techniques (instrumentation, methods)
• Tooth Root (drug effects, pathology)
• X-Ray Microtomography (methods)
• Young Adult