[Epidermolysis bullosa acquisita complicated by esophageal stenosis. Endoscopic treatment with thermoplastic dilators and intralesional steroid injection].

Abstract

Epidermolysis bullosa acquisita (EBA) is a rare auto-immune dermatologic disease, produced by auto-antibodies against colagen VII. We report a 44 years old male patient with EBA diagnosed 15 years before, who presented with progressive disphagia, being diagnosed an esophageal involvement of EBA. The patient was submitted to endoscopic treatment with thermoplastic bougie dilation and intralesional corticosteroid injection. The patient improved clinically with recovery of nutritional status. Esophageal involvement in EBA is very rare and its reason is still unknown. Endoscopic approach must be cautiously performed with the use of small diameter endoscopes, small caliber dilators, intralesional injection of corticosteroid and enteral tube in order to minimize the risks of complications, as well as esophageal rest from food trauma and better reparatory molding of the epithelium.

• Authors: E G Moura, D S Couto-Júnior, H Alvarado-Escobar, B da Costa-Martins, R A Sallum, E L Artifon, P Sakai
• Journal: Revista de gastroenterologia de Mexico (Rev Gastroenterol Mex) 2011 Jul-Sep Vol. 76 Issue 3 Pg. 279-85 ISSN: 0375-0906 [Print] Mexico
• Vernacular Title: Epidermólisis bullosa adquirida complicada por estenosis de esófago. Tratamiento endoscópico con sondas termoplásticas e inyección intralesional de corticoesteroide.
• PMID: 22041322 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Glucocorticoids
• Prednisone

Topics

• Adult
• Combined Modality Therapy
• Dilatation (instrumentation)
• Epidermolysis Bullosa Acquisita (complications)
• Esophageal Stenosis (etiology, therapy)
• Esophagoscopy
• Glucocorticoids (administration & dosage)
• Humans
• Injections, Intralesional
• Male
• Prednisone (administration & dosage)