Supramolecular hydrogelators of N-terminated dipeptides selectively inhibit cancer cells.

Abstract	Consisting of N-terminated diphenylalanine, a new type of supramolecular hydrogelators forms hydrogels within a narrow pH window (pH 5.0 to 6.0) and selectively inhibits growth of HeLa cells, which provides important and useful insights for designing molecular nanofibers as potential nanomedicines.
Authors	Yi Kuang, Yuan Gao, Bing Xu
Journal	Chemical communications (Cambridge, England) (Chem Commun (Camb)) Vol. 47 Issue 47 Pg. 12625-7 (Dec 21 2011) ISSN: 1364-548X [Electronic] England
PMID	22037699 (Publication Type: Journal Article, Research Support, N.I.H., Extramural)
Chemical References	Antineoplastic Agents Dipeptides Hydrogels phenylalanylphenylalanine Phenylalanine
Topics	Antineoplastic Agents (chemistry, pharmacology) Cell Proliferation (drug effects) Dipeptides HeLa Cells Humans Hydrogels (chemistry) Hydrogen-Ion Concentration Models, Molecular Molecular Conformation Nanomedicine Phenylalanine (analogs & derivatives, chemistry, pharmacology)

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