Long term hemodialysis spondylarthropathy: an atlanto-occipital location.

Abstract

A 41 years old patient on hemodialysis for 17 years with a clinical and radiological picture of osteoarticular beta 2 microglobulin amyloidosis, is presented. The patient had skeletal involvements, included cystic lesions of the left hip and both humeral heads and a C5/C6 spondylarthropathy. She had also associated carpal tunnel syndrome. Radiological exploration of the atlanto-occipital articulation demonstrated destructive changes. Histology documented osseous and periarticular deposition of beta 2 microglobulin derived amyloid. This is an unusual location of destructive spondylarthropathy in a patient on chronic hemodialysis.

• Authors: B Grignon, S Bracard, H Abadou, J Roland, L Picard
• Journal: Journal of neuroradiology = Journal de neuroradiologie (J Neuroradiol) Vol. 17 Issue 1 Pg. 60-5 (Jan 1990) ISSN: 0150-9861 [Print] France
• PMID: 2201755 (Publication Type: Case Reports, Journal Article)

Chemical References

• beta 2-Microglobulin

Topics

• Adult
• Amyloidosis (diagnosis, diagnostic imaging)
• Atlanto-Occipital Joint (pathology)
• Cervical Vertebrae (pathology)
• Female
• Humans
• Magnetic Resonance Imaging
• Renal Dialysis (adverse effects)
• Spinal Diseases (diagnosis, diagnostic imaging)
• Tomography, X-Ray Computed
• beta 2-Microglobulin