Cicatricial pemphigoid with linear IgA deposit.

Abstract

A Japanese woman with typical clinical and histological manifestations of cicatricial pemphigoid was presented. Direct immunofluorescent (IF) investigation of perilesional skin revealed in vivo deposits of IgA but not of IgG, IgM, or C3. Indirect IF study revealed that this patient had circulating antibody against epidermal basement membrane zone of the IgA class. We would like to classify this case as cicatricial pemphigoid with IgA deposits rather than as a cicatricial variant of linear IgA bullous dermatosis.

• Authors: K Tamaki, K Nashiro, A Ishii
• Journal: The Journal of dermatology (J Dermatol) Vol. 17 Issue 5 Pg. 317-21 (May 1990) ISSN: 0385-2407 [Print] England
• PMID: 2199546 (Publication Type: Case Reports, Journal Article)

Chemical References

• Immunoglobulin A

Topics

• Aged
• Female
• Fluorescent Antibody Technique
• Humans
• Immunoglobulin A (analysis)
• Pemphigoid, Benign Mucous Membrane (immunology)
• Skin Diseases, Vesiculobullous (immunology)