Abstract | BACKGROUND: Few studies have evaluated the significance of associated urological anomalies in vesicoureteral reflux (VUR). The aim of our study was to determine the incidence of associated urological anomalies in patients with high grade VUR and to assess their impact on renal parenchymal scarring. METHODS: We retrospectively reviewed the hospital records of 1,765 consecutive cases diagnosed with high grade VUR (Grade III-V) at our hospital between 1998 and 2010. The diagnosis of VUR was made by a voiding cystourethrogram (VCUG). Renal scarring was evaluated by dimercapto- succinic acid ( DMSA) scintigraphy and classified into three groups: mild (focal defects in uptake between 40 and 45%), moderate (uptake of renal radionuclide between 20 and 40%), and severe (shrunken kidney with relative uptake <20%). All associated urological anomalies were diagnosed by ultrasound or VCUG or DMSA scan. RESULTS: CONCLUSION: Associated urological anomalies occur commonly in patients with high grade VUR. Our data shows that nearly half of the patients with VUR and associated urological anomalies have renal scarring. Early recognition and treatment of VUR patients with associated urological anomalies may decrease the risk of renal parenchymal damage.
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Authors | Manuela Hunziker, Balazs Kutasy, Federica D'Asta, Prem Puri |
Journal | Pediatric surgery international
(Pediatr Surg Int)
Vol. 28
Issue 2
Pg. 201-4
(Feb 2012)
ISSN: 1437-9813 [Electronic] Germany |
PMID | 21994077
(Publication Type: Comparative Study, Journal Article)
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Topics |
- Child
- Child, Preschool
- Female
- Follow-Up Studies
- Humans
- Incidence
- Infant
- Ireland
(epidemiology)
- Male
- Prevalence
- Retrospective Studies
- Severity of Illness Index
- Urinary Tract
(abnormalities)
- Vesico-Ureteral Reflux
(congenital, diagnosis, epidemiology)
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