[Antibiotherapy in chronic familial granulomatosis].

Abstract

Antibacterial therapy in chronic granulomatous disease requires antimicrobials active on Staphylococcus aureus and enterobacteria, which also have a good intracellular penetration and activity as rifampicin, fluoroquinolone, fosfomycin, cotrimoxazole. Several trials showed that cotrimoxazole was effective for the prevention of bacterial infection: thus, this antimicrobial can be used as long-term and continuous prophylaxia. Fungal infections require the use of amphotericin B. The place of new imidazole compounds as itraconazole should be assessed.

• Authors: J L Vilde, C Leport
• Journal: Pathologie-biologie (Pathol Biol (Paris)) Vol. 38 Issue 4 Pg. 294-7 (Apr 1990) ISSN: 0369-8114 [Print] France
• Vernacular Title: Antibiothérapie au cours de la granulomatose chronique familiale.
• PMID: 2198524 (Publication Type: English Abstract, Journal Article, Review)

Chemical References

• Anti-Bacterial Agents
• Anti-Infective Agents
• Drug Combinations
• Amphotericin B
• Trimethoprim
• Sulfamethoxazole

Topics

• Amphotericin B (therapeutic use)
• Anti-Bacterial Agents (metabolism, therapeutic use)
• Anti-Infective Agents (therapeutic use)
• Bacterial Infections (complications, drug therapy)
• Drug Combinations (therapeutic use)
• Granulomatous Disease, Chronic (complications, genetics)
• Humans
• Mycoses (complications, drug therapy)
• Premedication
• Sulfamethoxazole (therapeutic use)
• Trimethoprim (therapeutic use)