Problems with clinical trials in general practice--a double-blind comparison of cream containing miconazole and hydrocortisone with hydrocortisone alone in the treatment of intertrigo.

Abstract	A double-blind comparative study between 1% hydrocortisone cream and a combination of 1% hydrocortisone cream and 2% miconazole cream has highlighted some of the problems with this type of research in general practice. The collection of adequate patient numbers within a predefined time scale proved a major problem. However, the study demonstrated the safety and efficacy of both these preparations in the treatment of intertrigo.
Authors	K Hedley, P Tooley, H Williams
Journal	The British journal of clinical practice (Br J Clin Pract) Vol. 44 Issue 4 Pg. 131-5 (Apr 1990) ISSN: 0007-0947 [Print] England
PMID	2196926 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Multicenter Study, Randomized Controlled Trial)
Chemical References	Drug Combinations Ointments Miconazole Hydrocortisone
Topics	Double-Blind Method Drug Combinations Family Practice Female Humans Hydrocortisone (therapeutic use) Intertrigo (drug therapy) Male Miconazole (therapeutic use) Multicenter Studies as Topic Ointments Randomized Controlled Trials as Topic

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