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Curative effect of topical treatment of digital dermatitis with a gel containing activated copper and zinc chelate.

Abstract
The efficacy of two topical treatments for painful ulcerative stage (M2) of bovine digital dermatitis (BDD) lesions was compared in a clinical trial conducted on five dairy farms in 2009 to 2010. The first treatment was a water-based gel with active components copper and zinc (Intra Hoof-fit gel [IHF]) and the second treatment was a topical chlortetracycline spray (CTC spray). The experimental unit for this study was the hindleg with the presence of a BDD lesion. Cure was defined as the transition of an M2 lesion into a healed (M0) or a non-painful chronic stage (M4) of BDD at D28. On day 0, cows with M2 BDD lesions were photographed and were treated with either IHF or CTC. Subsequently, feet were photographed and scored on D28. The cure rate of M2 BDD lesions treated with IHF at D28 was 0.92 (CI 0.84 to 0.96) and was significantly better than for M2 BDD lesions treated with CTC, which was 0.58 (CI 0.47 to 0.68).
AuthorsM Holzhauer, C J Bartels, M van Barneveld, C Vulders, T Lam
JournalThe Veterinary record (Vet Rec) Vol. 169 Issue 21 Pg. 555 (Nov 19 2011) ISSN: 2042-7670 [Electronic] England
PMID21957114 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Gels
  • Copper
  • Zinc
Topics
  • Administration, Topical
  • Animals
  • Cattle
  • Cattle Diseases (drug therapy)
  • Chelation Therapy (methods, veterinary)
  • Copper (administration & dosage, therapeutic use)
  • Digital Dermatitis (drug therapy)
  • Female
  • Gels
  • Hoof and Claw (drug effects, pathology)
  • Treatment Outcome
  • Zinc (administration & dosage, therapeutic use)

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