Abstract | BACKGROUND: CASE DESCRIPTION: We present a case of a 66-year-old woman affected by macroglossia due to light chain amyloidosis who presented with eating and breathing difficulties. Because of prior successful results of radiotherapy for localized amyloid disease, our patient was treated with external beam radiation therapy (20 Gy in 10 fractions). The treatment was well tolerated by the patient. However, her systemic amyloidosis progressed, with a subclinical increase in tongue width. CONCLUSIONS: This is the first reported use of radiotherapy for amyloidosis of the tongue. There was no evidence of benefit using a total dose of 20 Gy. This therapeutic modality is not recommended for the routine management of macroglossia.
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Authors | Isabelle Thibault, Isabelle Vallières |
Journal | Case reports in oncology
(Case Rep Oncol)
Vol. 4
Issue 2
Pg. 392-9
(May 2011)
ISSN: 1662-6575 [Electronic] Switzerland |
PMID | 21941488
(Publication Type: Case Reports)
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