Docetaxel-induced nail toxicity: a case of severe onycholysis and topic review.

Abstract	Docetaxel is a commonly-used anti-cancer chemotherapeutic agent given its efficacy in a large variety of solid tumors. It is associated with various adverse effects one of which is nail toxicity. We report a case of severe onycholysis as a result of treatment with docetaxel in a patient who suffered from metastatic nasopharyngeal carcinoma. The case report will be followed by a discussion on the possible mechanism and preventive strategies for taxane-induced nail toxicity.
Authors	Chi-Pan Lau, Pun Hui, Tak-Cheung Chan
Journal	Chinese medical journal (Chin Med J (Engl)) Vol. 124 Issue 16 Pg. 2559-60 (Aug 2011) ISSN: 2542-5641 [Electronic] China
PMID	21933605 (Publication Type: Case Reports, Journal Article, Review)
Chemical References	Taxoids Docetaxel
Topics	Adult Docetaxel Female Humans Nails (drug effects, pathology) Onycholysis (chemically induced) Taxoids (adverse effects)

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