[Study on the prevalence of acute flaccid paralysis and hand foot mouth disease in Beijing 2006 - 2008].

Abstract

OBJECTIVE:

To study the prevalence of acute flaccid paralysis (AFP) and hand foot mouth disease (HFMD) in Beijing, from 2006 - 2008.

METHODS:

Data on AFP and HFMD was analyzed epidemiologically, during 2006 - 2008 in Beijing. All the specimens from AFP cases were isolated and identified by RD and L20B cell and all of non-polio enterovirus (NPEV) cases were assayed by HFMD real-time PCR kit. The relationship between AFP and HFMD was analyzed.

RESULTS:

During 2006 - 2008, the number of AFP case in Beijing increased from 108 to 177 while the NPEV isolation rate increased from 11.11% to 20.34% and the positive rate of enterovirus 71 (EV71) and/or coxsackie virus A16 (Cox A16) increased from 0.93% to 10.17%.

CONCLUSION:

The prevalence of HFMD caused by EV71 and/or Cox A16 might have contributed to the increase of AFP cases in Beijing.

• Authors: Ming Luo, Cheng Gong, Tie-gang Zhang, Zhu-jia-zi Zhang
• Journal: Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi (Zhonghua Liu Xing Bing Xue Za Zhi) Vol. 32 Issue 7 Pg. 681-4 (Jul 2011) ISSN: 0254-6450 [Print] China
• PMID: 21933539 (Publication Type: English Abstract, Journal Article)

Topics

• Child, Preschool
• China (epidemiology)
• Enterovirus A, Human (isolation & purification)
• Female
• Hand, Foot and Mouth Disease (epidemiology, virology)
• Humans
• Infant
• Infant, Newborn
• Male
• Movement Disorders (epidemiology, virology)
• Paralysis (epidemiology, virology)
• Prevalence