Abstract | PURPOSE: SETTING: Private ophthalmic clinic. DESIGN: Case series. METHOD: Consecutive patients who had PRK augmented with topical mitomycin-C (MMC) after PKP for keratoconus were retrospectively reviewed. Patients were divided into a a low cylinder group (refractive cylinder ≤ 6.00 D) and a high cylinder group (refractive cylinder >6.00 D). Visual acuity, refraction, and keratometry were analyzed preoperatively and 1, 3, 6, and 12 months postoperatively. RESULTS: The study comprised 47 eyes (41 patients). The spherical equivalent (SE) decreased from -4.24 D ± 3.23 (SD) preoperatively to -0.71 ± 1.03 D 12 months postoperatively in the low cylinder group and from -4.19 ± 3.54 D to -2.45 ± 3.42 D, respectively, in the high cylinder group. The refractive cylinder decreased from -4.27 ± 1.4 D to -1.71 ± 1.55 D, respectively, in the low cylinder group and from -7.78 ± 1.21 D to -4.6 ± 2.54 D, respectively, in the high cylinder group. By the last follow-up, 8.3% of patients had lost 2 lines of corrected distance visual acuity. There were no cases of corneal haze greater than 2+ or of graft rejection. CONCLUSIONS: FINANCIAL DISCLOSURE: No author has financial or proprietary interests in any material or method mentioned.
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Authors | Chris Hodge, Gerard Sutton, Michael Lawless, Chris Rogers |
Journal | Journal of cataract and refractive surgery
(J Cataract Refract Surg)
Vol. 37
Issue 10
Pg. 1884-94
(Oct 2011)
ISSN: 1873-4502 [Electronic] United States |
PMID | 21930049
(Publication Type: Journal Article)
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Copyright | Copyright © 2011 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved. |
Chemical References |
- Alkylating Agents
- Mitomycin
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Topics |
- Adult
- Aged
- Alkylating Agents
(administration & dosage)
- Combined Modality Therapy
- Female
- Follow-Up Studies
- Humans
- Keratoconus
(physiopathology, surgery)
- Keratoplasty, Penetrating
- Male
- Middle Aged
- Mitomycin
(administration & dosage)
- Photorefractive Keratectomy
- Postoperative Care
- Refraction, Ocular
(physiology)
- Refractive Surgical Procedures
- Retrospective Studies
- Treatment Outcome
- Visual Acuity
(physiology)
- Young Adult
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