Abstract | AIM: To describe the symptoms, clinical management and short-term outcome in a series of paediatric oncology patients with severe typhlitis following conservative treatment. METHODS: Twelve episodes of severe typhlitis in 11 children with cancer treated at the paediatric oncology ward at Queen Silvias Children's Hospital between 1995 and 2006 were analysed retrospectively. Data on symptoms, radiological findings, laboratory status and treatment as well as outcome were collected and analysed. RESULTS: In all episodes, the classical signs of neutropenia, fever, abdominal pain and thickening of the bowel wall were present. All were successfully treated with bowel rest, broadspectrum antibiotics and supportive care. After recovery from typhlitis, three patients needed surgical intervention because of complications. CONCLUSION:
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Authors | Nicklas Sundell, Håkan Boström, Mats Edenholm, Jonas Abrahamsson |
Journal | Acta paediatrica (Oslo, Norway : 1992)
(Acta Paediatr)
Vol. 101
Issue 3
Pg. 308-12
(Mar 2012)
ISSN: 1651-2227 [Electronic] Norway |
PMID | 21910749
(Publication Type: Evaluation Study, Journal Article)
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Copyright | © 2011 The Author(s)/Acta Paediatrica © 2011 Foundation Acta Paediatrica. |
Chemical References |
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Topics |
- Adolescent
- Antineoplastic Agents
(therapeutic use)
- Child
- Child, Preschool
- Enterocolitis, Neutropenic
(complications, diagnosis, therapy)
- Female
- Humans
- Infant
- Male
- Neoplasms
(complications, drug therapy)
- Retrospective Studies
- Treatment Outcome
- Typhlitis
(complications, diagnosis, therapy)
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