Posterior capsule opacification and capsular bag performance of a microincision intraocular lens.

Abstract

PURPOSE:

To assess the axial stability and posterior capsule opacification (PCO)-inhibiting efficacy of a microincision hydrophilic intraocular lens (IOL) (Idea 613 XC) and a standard hydrophobic open-loop acrylic IOL (Acrysof SA60AT).

SETTING:

Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom.

DESIGN:

Clinical trial.

METHODS:

Patients with bilateral cataract received a microincision cataract surgery (MICS) IOL in 1 eye and a small-incision cataract surgery (SICS) IOL in the contralateral eye. Follow-up examinations were performed immediately after surgery and postoperatively at 1 week and 3 and 24 months. Posterior capsule opacification was assessed using retroillumination photography. Anterior chamber depth (ACD) was measured using partial coherence laser interferometry, and IOL tilt and decentration were measured using a Purkinje meter.

RESULTS:

Seventy eyes (35 patients) were enrolled. The mean ACD at 3 months was 4.91 mm ± 0.26 (SD) in the MICS group and 4.60 ± 0.23 mm in the SICS group. The anterior IOL shift over the first 3 months was slightly smaller with the MICS IOL (81 μm) than with the SICS IOL (254 μm). The mean ACD was 0.377 ± 178 μm deeper with the MICS IOL (P<.01, paired t test). Two years postoperatively, the amount of regeneratory PCO was higher with the MICS IOL than with the SICS IOL (image analysis software score 2.6 versus 1.9; P=.005).

CONCLUSIONS:

Two years after surgery, the PCO rate was slightly higher with the MICS IOL. The 2 IOLs had similar performance in terms of axial stability, decentration, and tilt.

FINANCIAL DISCLOSURE:

No author has a financial or proprietary interest in any material or method mentioned. Additional disclosures are found in the footnotes.

• Authors: Vinod Gangwani, Nino Hirnschall, John Koshy, Alja Crnej, Yutaro Nishi, Vincenzo Maurino, Oliver Findl
• Journal: Journal of cataract and refractive surgery (J Cataract Refract Surg) Vol. 37 Issue 11 Pg. 1988-92 (Nov 2011) ISSN: 1873-4502 [Electronic] United States
• PMID: 21907536 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2011 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

Topics

• Aged
• Aged, 80 and over
• Anterior Chamber (pathology)
• Capsule Opacification (etiology, surgery)
• Double-Blind Method
• Female
• Follow-Up Studies
• Humans
• Interferometry
• Laser Therapy
• Lasers, Solid-State
• Lens Implantation, Intraocular
• Lenses, Intraocular (adverse effects)
• Light
• Male
• Microsurgery (methods)
• Middle Aged
• Phacoemulsification (methods)
• Posterior Capsule of the Lens (pathology)
• Prosthesis Design
• Pseudophakia (physiopathology)
• Refraction, Ocular (physiology)
• Visual Acuity (physiology)