Abstract | OBJECTIVE: To investigate the clinicopathological characteristics of large cell calcifying Sertoli cell tumor (LCCSCT) of the testis. METHODS: We studied a case of LCCSCT by light microscopy, Western blotting and immunohistochemistry, reviewed relevant literature, and analyzed the clinical, morphological and immunohistochemical features, treatment and prognosis of the tumor. RESULTS: The patient was a 25 years old man. Pathohistologically, the tumor was characterized by a mass of polygonal tumor cells in a tubular and trabecular growth pattern, with abundant acidophilic cytoplasm, enlarged vesicular nuclei, and extensive calcified debris in stroma. The tumor cells were positive for inhibin, S-100, vimentin and alcian blue, but negative for PLAP, SMA, CK, AFP and periodic acid-Schiff (PAS) reaction. CONCLUSION:
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Authors | Jin-Feng Zheng, Tong-Da Cheng, Xiao-Hong Liu, Hong-Biao Jing, Ming Geng, Yong-Cheng Cao, Yi Liu |
Journal | Zhonghua nan ke xue = National journal of andrology
(Zhonghua Nan Ke Xue)
Vol. 17
Issue 8
Pg. 730-3
(Aug 2011)
ISSN: 1009-3591 [Print] China |
PMID | 21898998
(Publication Type: Case Reports, English Abstract, Journal Article)
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Topics |
- Adult
- Humans
- Male
- Sertoli Cell Tumor
(pathology)
- Sex Cord-Gonadal Stromal Tumors
(pathology)
- Testicular Neoplasms
(pathology)
- Testis
(pathology)
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