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Effect of tianeptine on cognitive functions in patients with depressive disorders during a 3-month observation.

AbstractOBJECTIVE:
The authors put forward the hypotheses that during a three-month treatment with tianeptine in patients with depressive disorders there is an improvement in the short-term memory, reaction time and attention.
SUBJECT AND METHODS:
20 patients suffering from depression, were included in the study. During the entire research period all patients were treated with monotherapy with tianeptine. Cognitive function measurements were performed using the Vienna Test System.
RESULTS:
Our study showed an improvement in the all the assessed functions: patients treated with tianeptine had better performance in tests measuring short term memory and learning processes as well as reaction time and attention.
CONCLUSION:
In conclusion, the study shows that tianeptine improves cognitive functions in depressed patients.
AuthorsAdam Klasik, Krzysztof Krysta, Irena Krupka-Matuszczyk
JournalPsychiatria Danubina (Psychiatr Danub) Vol. 23 Suppl 1 Pg. S18-22 (Sep 2011) ISSN: 0353-5053 [Print] Croatia
PMID21894095 (Publication Type: Journal Article)
Chemical References
  • Antidepressive Agents, Tricyclic
  • Thiazepines
  • tianeptine
Topics
  • Adolescent
  • Adult
  • Antidepressive Agents, Tricyclic (pharmacology)
  • Attention (drug effects)
  • Cognition (drug effects)
  • Depressive Disorder (drug therapy)
  • Female
  • Follow-Up Studies
  • Humans
  • Learning (drug effects)
  • Male
  • Memory, Short-Term (drug effects)
  • Middle Aged
  • Psychomotor Performance (drug effects)
  • Reaction Time (drug effects)
  • Thiazepines (pharmacology)
  • Young Adult

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