Abstract | BACKGROUND: Adipose tissue functions as an endocrine organ by releasing adipokines which have important roles in the regulation of inflammation and insulin sensitivity. Although there is evidence of improvement in circulating levels of adipokines with weight loss, few studies relate such changes to specific diets. We investigated the effects of weight loss achieved by two different diets on circulating adipokine levels in obese individuals. METHODS: A total of 120 obese patients (body mass index ≥ 35 kg/m(2)) underwent a three-month screening period on a low-fat, reduced-calorie diet. Patients failing to achieve a 5% weight loss using this approach were randomly allocated to either a low carbohydrate/high protein diet (n = 17) or to a commercial very low calorie diet (LighterLife(®), n = 14) for a period of nine months. RESULTS: CONCLUSION:
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Authors | Catherine Rolland, Michelle Hession, Iain Broom |
Journal | Diabetes, metabolic syndrome and obesity : targets and therapy
(Diabetes Metab Syndr Obes)
Vol. 4
Pg. 315-23
( 2011)
ISSN: 1178-7007 [Electronic] New Zealand |
PMID | 21887104
(Publication Type: Journal Article)
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