Efficacy of ribavirin in a case of long lasting and disabling Gianotti-Crosti syndrome.

Abstract

BACKGROUND:

Gianotti-Crosti syndrome, also known as papular acrodermatitis of childhood, is an acrally distributed papular eruption occurring mostly in infants and young children.

MAIN OBSERVATIONS:

A six-year-old girl presented to us with four-month history of a generalized intensely pruritic rash, clinically consistent with Gianotti-Crosti syndrome, following a febrile illness with common cold symptoms. Clinical remission was not achieved despite of several medications. With reluctance and parent's informed consent, we commenced a course of oral ribavirin syrup at a dose of 300mg daily for five days. Dramatic symptomatic remission was noted five days later.

CONCLUSION:

Further studies are needed to confirm the efficacy of ribavirin in Gianotti-Crosti syndrome.

• Authors: Vijay Zawar, Antonio Chuh
• Journal: Journal of dermatological case reports (J Dermatol Case Rep) Vol. 2 Issue 4 Pg. 63-6 (Dec 27 2008) ISSN: 1898-7249 [Print] Poland
• PMID: 21886717 (Publication Type: Case Reports)