Abstract | BACKGROUND: PATIENTS AND METHODS: RESULTS: Eighteen patients were enrolled in this study. Eight patients had measurable lymph node metastases by the RECIST criteria and computed tomography (CT) showed that five (62.5%) displayed a major response to the treatment. Out of 18 patients, 14 (78%) showed negative results on peritoneal cytology and no macroscopic PC, while the remaining four were cancer cell positive on peritoneal cytology or showed macroscopic PC even after NIPS. The median survival time of the entire group was 24.6 months. No treatment-related mortality was observed during NIPS and surgery. CONCLUSION: This study indicated that the NIPS combined with surgery was highly active and well tolerated by advanced gastric cancer patients with PC.
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Authors | Yoshiyuki Fujiwara, Shuji Takiguchi, Kiyokazu Nakajima, Hiroshi Miyata, Makoto Yamasaki, Yukinori Kurokawa, Masaki Mori, Yuichiro Doki |
Journal | Journal of surgical oncology
(J Surg Oncol)
Vol. 105
Issue 1
Pg. 38-42
(Jan 2012)
ISSN: 1096-9098 [Electronic] United States |
PMID | 21882194
(Publication Type: Journal Article)
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Copyright | Copyright © 2011 Wiley Periodicals, Inc. |
Chemical References |
- Drug Combinations
- Taxoids
- S 1 (combination)
- Tegafur
- Docetaxel
- Oxonic Acid
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Topics |
- Aged
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Chemotherapy, Adjuvant
- Combined Modality Therapy
- Docetaxel
- Drug Combinations
- Female
- Follow-Up Studies
- Humans
- Injections, Intraperitoneal
- Lymphatic Metastasis
- Male
- Middle Aged
- Neoplasm Staging
- Oxonic Acid
(administration & dosage)
- Peritoneal Neoplasms
(drug therapy, secondary, surgery)
- Postoperative Complications
- Prospective Studies
- Stomach Neoplasms
(drug therapy, pathology, surgery)
- Survival Rate
- Taxoids
(administration & dosage)
- Tegafur
(administration & dosage)
- Treatment Outcome
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