Abstract | OBJECTIVE: METHODS: Normal adult pigs were subjected to saline lavage of the bilateral lungs to induce acute lung injury and randomized subsequently into 3 groups for treatment with inhalation of perfluorocarbon, combined inhalation of perfluorocarbon and tetramethylpyrazine, or inhalation of tetramethylpyrazine. The changes of mean arterial pressure (MAP), PetCO(2), mPAP, CVP and PAWP were recorded at different time points following the lung injury, and the lung tissues were sampled for histological observations. RESULTS: CONCLUSION:
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Authors | Xue-mei Peng, Juan-hua Xie, Bing Shuai, Yan-lan Li, Zhong-hong Wang, Hua-dong Wang, Yan-ping Wang |
Journal | Nan fang yi ke da xue xue bao = Journal of Southern Medical University
(Nan Fang Yi Ke Da Xue Xue Bao)
Vol. 31
Issue 8
Pg. 1382-6
(Aug 2011)
ISSN: 1673-4254 [Print] China |
PMID | 21868329
(Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Fluorocarbons
- Pyrazines
- tetramethylpyrazine
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Topics |
- Acute Lung Injury
(drug therapy, etiology, pathology)
- Administration, Inhalation
- Animals
- Drug Therapy, Combination
- Fluorocarbons
(administration & dosage)
- Hemodynamics
(drug effects)
- Lung
(pathology)
- Phytotherapy
- Pyrazines
(administration & dosage)
- Swine
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