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[Efficacity of rituximab in hemolytic anemia with cold autoantibodies case].

AbstractINTRODUCTION:
Autoimmune hemolytic anemia with cold autoantibodies or cold agglutinin disease is a rare chronic disorder in which no treatment has, until now, evidence of its effectiveness.
CLINICAL CASE:
We report a patient who successfully responded to rituximab for a cold agglutinin disease refractory to conventional therapy with very good tolerance and a complete remission.
CONCLUSION:
There are only few observations that have been reported in the literature regarding the efficacity of rituximab in the treatment of cold agglutinin disease. This promising therapy could, in the future, constitute a real alternative.
AuthorsY Sekkach, S Hammi, M Elqatni, J Fatihi, N Elomri, F Mekouar, M Badaoui, M Jira, J Smaali, A El Khattabi, T Amezyane, A Abouzahir, D Ghafir
JournalAnnales pharmaceutiques francaises (Ann Pharm Fr) Vol. 69 Issue 4 Pg. 205-8 (Jul 2011) ISSN: 0003-4509 [Print] France
Vernacular TitleEfficacité exemplaire du rituximab dans un cas d'anémie hémolytique à autoanticorps froids.
PMID21840439 (Publication Type: Case Reports, English Abstract, Journal Article)
CopyrightCopyright © 2011 Elsevier Masson SAS. All rights reserved.
Chemical References
  • Antibodies, Monoclonal, Murine-Derived
  • Antineoplastic Agents
  • Rituximab
Topics
  • Anemia, Hemolytic, Autoimmune (drug therapy)
  • Antibodies, Monoclonal, Murine-Derived (therapeutic use)
  • Antineoplastic Agents (therapeutic use)
  • Drug Resistance
  • Humans
  • Male
  • Middle Aged
  • Rituximab

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