Developmental genetics in Xenopus tropicalis.

Abstract

The diploid pipid frog Xenopus tropicalis has recently emerged as a powerful new model system for combining genetic and genomic analysis of tetrapod development with embryological and biochemical assays. Its early development closely resembles that of its well-understood tetraploid relative Xenopus laevis, from which techniques and reagents can be readily transferred, but its compact genome is highly syntenic with those of amniotes. Genetic approaches are facilitated by the large number of embryos produced and the ease of haploid genetics and gynogenesis.

• Authors: Timothy J Geach, Lyle B Zimmerman
• Journal: Methods in molecular biology (Clifton, N.J.) (Methods Mol Biol) Vol. 770 Pg. 77-117 ( 2011) ISSN: 1940-6029 [Electronic] United States
• PMID: 21805262 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• DNA, Complementary
• Genetic Markers

Topics

• Animals
• Breeding
• Centromere (genetics)
• Cryopreservation
• DNA, Complementary (genetics)
• Embryo, Nonmammalian (metabolism)
• Female
• Fertilization in Vitro
• Genetic Linkage
• Genetic Markers (genetics)
• Genetic Techniques
• Genomics
• Genotype
• Haploidy
• Karyotyping
• Male
• Mutagenesis
• Mutation
• Phenotype
• Polymorphism, Single Nucleotide (genetics)
• Reproduction, Asexual
• Silver Staining
• Spermatozoa (metabolism)
• Tissue and Organ Harvesting
• Xenopus (embryology, genetics, growth & development, physiology)