HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Liver transplantation for acute hepatic failure due to chemotherapy-induced HBV reactivation in lymphoma patients.

Abstract
Hepatitis B (HBV) reactivation induced by chemotherapy is problem encountered recently in the management of malignant diseases. Chemotherapy-induced HBV reactivation may ultimately lead to terminal acute liver failure. Liver transplantation (LT) currently remains the only definitive treatment option for such cases, but is generally denied to patients suffering from malignancy. Here, the authors describe 2 cases of cancer-free and HBV graft re-infection-free survival after LT performed for terminal liver failure arising from HBV reactivation induced by chemotherapy for advanced stage lymphoma. These 2 cases, and some other reports in the literature, may suggest that patients suffering from hematologic malignancies and terminal liver disease can be considered for LT if the prognosis of their hematologic malignancy is good.
AuthorsTimothée Noterdaeme, Luc Longrée, Christian Bataille, Arnaud Deroover, Anne Lamproye, Jean Delwaide, Yves Beguin, Pierre Honoré, Olivier Detry
JournalWorld journal of gastroenterology (World J Gastroenterol) Vol. 17 Issue 25 Pg. 3069-72 (Jul 07 2011) ISSN: 2219-2840 [Electronic] United States
PMID21799656 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antineoplastic Agents
Topics
  • Antineoplastic Agents (therapeutic use)
  • Female
  • Hepatitis B (drug therapy, virology)
  • Hepatitis B virus (physiology)
  • Humans
  • Liver Failure, Acute (surgery, virology)
  • Liver Transplantation
  • Lymphoma (drug therapy, virology)
  • Male
  • Middle Aged
  • Virus Activation

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: