[Efficiancy Angiotensin -converting enzyme inhibitors for the clinical practice].

Abstract

These clinical trials show the efficiency of therapy with angiotensin-converting enzyme (ACE) inhibitors in essential hypertension (EH), chronic heart failure and coronary heart disease (CHD). The SMILE studies have indicated positive results of the early administration (<24 hours) of zofenopril in patients with acute myocardial infarction (AMI). These results have been confirmed in high-risk patients, including those with hypertension and diabetes mellitus, which enables zofenopril to be recommended for clinical use in patients with EH and CHD. Zofenopril has a better safety profile than other agents.

• Authors: G V Abuladze, M I Nebieridze, E V Narsiia, I G Erkomaishvili, N G Pipiia
• Journal: Georgian medical news (Georgian Med News) Issue 195 Pg. 37-40 (Jun 2011) ISSN: 1512-0112 [Print] Georgia (Republic)
• PMID: 21778538 (Publication Type: English Abstract, Journal Article, Review)

Chemical References

• Angiotensin-Converting Enzyme Inhibitors
• Antihypertensive Agents
• zofenopril
• Captopril

Topics

• Angiotensin-Converting Enzyme Inhibitors (therapeutic use)
• Antihypertensive Agents (therapeutic use)
• Captopril (analogs & derivatives, chemistry, therapeutic use)
• Clinical Trials as Topic
• Diabetic Cardiomyopathies (complications, therapy)
• Heart Failure (drug therapy)
• Humans
• Hypertension (drug therapy)
• Myocardial Infarction (drug therapy)