Simultaneous necrotizing glomerulonephritis and Hodgkin's lymphoma: a case report and review of the literature.

Abstract

Glomerulonephritis occurs in 1% of Hodgkin's lymphoma patients. In the even rarer setting of rapidly progressive glomerulonephritis, lymphoma may go unrecognized. We describe a case of necrotizing glomerulonephritis in which treatment with cyclophosphamide and steroids led to resolution of lymphadenopathy. Two years later, recrudescent lymphadenopathy was shown to be Hodgkin's lymphoma, but renal disease did not recur.

• Authors: Thomas D Barbour, Richard J Haynes, Ian S D Roberts, Christopher G Winearls
• Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (Nephrol Dial Transplant) Vol. 26 Issue 10 Pg. 3403-8 (Oct 2011) ISSN: 1460-2385 [Electronic] England
• PMID: 21778279 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Cyclophosphamide
• Prednisolone

Topics

• Aged
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Cyclophosphamide (administration & dosage)
• Diagnosis, Differential
• Female
• Glomerulonephritis (complications, diagnosis, drug therapy)
• Hodgkin Disease (complications, diagnosis, drug therapy)
• Humans
• Prednisolone (administration & dosage)
• Prognosis